| 3 / 2 week 10 | E.T. - Katy Perry feat. Kanye West Capitol - 388.000 - 1 week at No.1 | |
| 2 / 1 week 9 | On The Floor - Jennifer Lopez feat. Pitbull Def Jam / Island - 373.000 | |
| 6 / 6 week 15 | Rolling In The Deep - Adele XL Recordings - 332.000 - Largest Points Increase | |
| 5 / 4 week 8 | Just Can't Get Enough - Black Eyed Peas Interscope - 309.000 | |
| 1 / 5 week 12 | S&M - Rihanna (feat. Britney Spears) Def Jam - 305.000 |
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| 4 / 3 week 11 | Born This Way - Lady GaGa 2 Interscope - 262.000 |
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| 7 / 8 week 12 | Price Tag - Jessie J feat. B.o.B. Island / Lava - 249.000 | |
| 9 / - week 2 | Judas - Lady GaGa Interscope - 227.000 | |
| 11 / 15 week 4 | Party Rock Anthem - LMFAO feat. Lauren Bennett & GoonRock Interscope - 193.000 | |
| 10 / 10 week 8 | Till The World Ends - Britney Spears Jive - 193.000 | |
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| 22 / 37 week 3 | The Lazy Song - Bruno Mars Elektra / Warner Bros. - 186.000 | |
| 8 / 7 week 23 | Grenade - Bruno Mars 3Elektra / Warner Bros. - 172.000 |
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| 14 / 21 week 4 | Sweat - Snoop Dogg vs. David GuettaPriority / Capitol - 148.000 | |
| 12 / 9 week 14 | F**kin' Perfect - Pink LaFace / Zomba - 146.000 |
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| 20 / 20 week 9 | Blow - Ke$ha Jive / RCA - 140.000 | |
| 18 / 22 week 8 | Down On Me - Jeremih feat. 50 CentDef Jam / Island - 130.000 | |
| 21 / 16 week 12 | I Need A Doctor - Dr.Dre feat. Eminem & Skylar Grey Interscope - 125.000 | |
| 16 / 11 week 27 | Firework - Katy Perry 3Capitol - 122.000 |
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| 13 / 12 week 15 | What The Hell - Avril Lavigne RCA - 122.000 |
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| 19 / 17 week 34 | F**k You! - Cee Lo Green 2Elektra / Warner Bros. - 121.000 | |
| 15 / 13 week 18 | Coming Home - Diddy Dirty Money Bad Boy / Interscope - 118.000 |
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| 25 / 23 week 9 | Look At Me Now - Chris Brown feat. Lil Wayne & Busta Rhymes Jive - 116.000 | |
| 23 / 25 week 3 | Give Me Everything - Pitbull feat. Ne-Yo, Afrojack & Nayer J Records - 116.000 | |
| 27 / 31 week 9 | Written In The Stars - Tinie Tempah (feat. Eric Turner) Parlophone - 116.000 | |
| 17 / 14 week 22 | Tonight (I'm F**kin' You) - Enrique Iglesias feat. Ludacris Polydor / Universal - 115.000 |
|
| | T.W.L. - Kanjani 8 Teichiku Entertainment Japan - 113.000 - Hot Shot Debut | |
| 26 / 19 week 14 | More - Usher Laface / Arista - 105.000 |
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| 24 / 18 week 19 | Yeah Yeah Yeah - Chris Brown Jive - 93.000 |
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| 28 / 27 week 5 | All Of The Lights - Kanye West Roc-A-Fella - 91.000 |
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| | The Show Goes On - Lupe Fiasco Atlantic - 90.000 | |
| 31 / 30 week 16 | Hello - Martin Solveig & Dragonette Temps D'avance / Big Beat Records - 87.000 |
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| 29 / 24 week 22 | Black And Yellow - Wiz Khalifa Atlantic - 82.000 |
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| | Run This World (Girls) - Beyoncé Columbia - 81.000 | |
| 30 / 26 week 37 | Just The Way You Are - Bruno Mars 4Elektra / Warner Bros. - 79.000 |
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| 32 / 29 week 10 | Someone Like You - Adele XL Recordings - 74.000 | |
| - / - week 3 | Who Says - Selena Gomez & The Scene Hollywood - 73.000 | |
| | Beautiful People - Chris Brown feat. Benny Benassi Jive - 71.000 | |
| 34 / 33 week 17 | Higher - Taio Cruz feat. Kylie Minogue (feat. Travie McCoy) Island - 70.000 | |
| 37 / 40 week 21 | Who's That Chick? - David Guetta feat. Rihanna Positiva / Virgin - 69.000 | |
| 38 / 35 week 21 | Hey Baby (Drop It To The Floor) - Pitbull feat. T-Pain J Records - 68.000 |